Ant-GTP

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C₁₇H₂₁N₆O₁₅P₃ (free acid)

Molecular Weight: 642.30 g/mol (free acid)

Exact Mass: 642.03 g/mol (free acid)

CAS#: 85287-50-9 (3'-isomer)

Purity: ≥ 95 % (HPLC)

Form: solution in water

Color: colorless to slightly yellow

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λ_max 258/332 nm, ε 9.8/4.6 L mmol^-1 cm^-1 (Tris-HCl pH 7.5), λ_exc 332 nm, λ_em 423 nm

BIOZ Product Citations:

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Selected References:
Gunawardana et al. (2015) Efficient preparation and properties of mRNAs containing a fluorescent cap analog: Anthraniloyl-m⁷GpppG Translation (Austin). 3 (1):e988538.
Pinto et al. (2011) Structure-activity relationships for the interactions of 2'- and 3'- (O)- (N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases. Biochem. Pharmacol. 82 (4):358.
Taha et al. (2009) Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2’ (3’)-O- (N- (methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides. Molecular Pharmacology 75 (3):693.
Goettle et al. (2007) Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides. Molecular Pharmacology 72 (3):526.