The SWISSCI MRC Under Oil 96 well Crystallization plate was developed at the MRC Laboratory of Molecular Biology (Cambridge, UK) in collaboration with Dr. Jan Löwe and colleagues.
The plate offers unique properties that make it ideal for both nanolitre crystallisation screening and microlitre optimisation alike. Made from optically superior polymer and with a new design of the wells, the plate allows easy crystal viewing and retrieval.
The new MRC Under Oil 96 well Crystallisation plate uses proprietary oil specially selected for the purpose of running macromolecular crystallisation under oil. Following the initial experiment, the solution under the oil is sequentially allowed to evaporate as a second stage enabling further crystal growth as a consequence of concentration. This is different from other experiments in that the conditions are then extreme in nature and permit new conditions to arise.