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West Nile Virus Pre-MHis


recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-1274 100 μg 300,70 Add to Basket/Quote Add to Notepad

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Purity: > 95 % (SDS-PAGE)

Form: liquid (Supplied in 20 mM phosphate buffer pH 7.5)

Antigen in ELISA and Western Blots, excellent antigen for detection of West-Nile virus with minimal specificity problems.

The E. coli derived recombinant protein contains the West-Nile N-Terminal Pre-M Virus immunodominant regions. The protein is fused with 6xHis tag.
West Nile virus (WNV) is a virus of the family Flaviviridae part of the Japanese encephalitis (JE) antigenic complex of viruses. Image reconstructions and cryoelectron microscopyreveal a 45-50 nm virion covered with a relatively smooth proteinsurface. This structure is similar to virus, both belong to the genus flavivirus within the family Flaviviridae. WNV is a positive-sense, single strand of RNA, it is between 11,000 and 12,000 nucleotides long which encode seven non-structural proteins and three structural proteins. The RNA strand is held within a nucleocapsid formed from 12 kDa protein blocks, the capsid is contained within a host-derived membrane altered by two viral glycoproteins.
The protein is purified by proprietary chromatographic technique.

BIOZ Product Citations:

Selected References:
Wengler (1989) Cell-associated West Nile flavivirus is covered with E+pre-M protein heterodimers which are destroyed and reorganized by proteolytic cleavage during virus release. J Virol. 63:2521.