Cell division cycle phosphatase
human, recombinant, E. coli
Cat. No. | Amount | Price (EUR) | Buy / Note |
---|---|---|---|
PR-348 | 20 μg | 286,30 | Add to Basket/Quote Add to Notepad |
For general laboratory use.
Shipping: shipped on dry ice
Storage Conditions: store at -80 °C
avoid freeze/thaw cycles
Shelf Life: 12 months
Molecular Weight: 68 kDa
Accession number: M81933
Purity: > 90 % (SDS-PAGE)
Form: liquid (Supplied in 20 mM Tris-HcL pH 8.0, 100 mM NaCl, 1 mM EDTA and 1 mM DTT)
Activity: 1 nmol of Cdc25A will hydrolyze 10 nmol of pNPP per minute at 37°C at pH 8.0.
Description:
The dual specific Cdc25A (Cell division cycle) phosphatase regulates cell cycle progression, has oncogenic and anti-apoptotic activity, and is overexpressed in many human tumors. The protein does not have tags.
Assay buffer: 50 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mM EDTA.
BIOZ Product Citations:
Selected References:
Fauman et al. (1998) Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A. Cell 93:617.
Gottlin et al. (1996) Kinetic analysis of the catalytic domain of human cdc25B. J. Biol. Chem. 271:27445.