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Rab32

Ras-associated, small GTP-binding protein

human, recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-194 50 μg 212,18 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Accession number: NP_006825

Accession number: NP_006825

Purity: > 90 % (SDS-PAGE)

Form: liquid (Supplied in 25 mM Hepes pH 7.2, 40 mM NaCl, 2 mM MgCl2, 10 μM GDP and 1 mM β-mercaptoethanol)

Activity: 100 pmol of protein can bind > 80 pmol of GDP.

Description:
Rab32 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab 32 is localized in perinuclear vesicles and mitochondria and regulates melanosome transport and mitochondrial fission.It may participate in adaptation to changing energy requirements during growth.

Selected References:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071.
Yamaguchi et al. (2002) A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc. Natl. Acad. Sci. USA. 99:14536.