Adenosine-5'-[( β,γ )-imido]triphosphate, P3-(1-(2-nitrophenyl)-ethyl)-ester, Triethylammonium salt
For research use only!
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 6 months after date of delivery
Molecular Formula: C18H24N7O14P3 (free acid)
Molecular Weight: 655.35 g/mol (free acid)
Exact Mass: 655.06 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 260 nm, ε 18.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Agonistic ligand, mainly for nucleoside receptor A1
Nucleosidephosphates stabilized against hydrolytic degradation can directly bind to nucleoside receptors. The caged form is protected during uptake and transport in animal experiments and can be well-directed released through activation at the target tissue.
BIOZ Product Citations:
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Volonte et al. (2009) Membrane components and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters. FEBS J. 276:318.
Yegutkin (2008) Nucleotide and nucleoside converting enzymes: Important modulators of purinergic signalling cascade. Biochim. Biophys. Acta 1783:673.
Williams et al. (1986) Effects of purine nucleotides on the binding of [3H]cyclopentyladenosine to adenosine A1-receptors in rat brain membranes. J. Neurochem. 47 (1):88.