Uridine-5'-(β-thio)-diphosphate, Sodium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 6 months after date of delivery
Molecular Formula: C9H14N2O11P2S (free acid)
Molecular Weight: 420.22 g/mol (free acid)
Exact Mass: 419.98 g/mol (free acid)
Purity: ≥ 90 % (HPLC)
Spectroscopic Properties: λmax 262 nm, ε 10.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Ligand for purinergic receptors:
Selective agonist at P2Y6[1,2] receptors
Please note: For reasons of stability, please make sure that the pH value of a solution of this product never drops below 7.0. This can be achieved by dissolving the nucleotide in a buffer of your choice (50 - 100 mM, pH 7 - 10). Dissolve and adjust concentration photometrically.
 Malmsjö et al. (2003) The stable pyrimidines UDPbetaS and UTPgammaS discriminate between contractile cerebrovascular P2 receptors. J. Pharmacol. 458 (3):305.
 Malmsjö et al. (2000) Characterization of contractile P2 receptors in human coronary arteries by use of the stable pyrimidines uridine 5'-O-thiodiphosphate and uridine 5'-O-3-thiotriphosphate. J. Pharmacol. Exp. Ther. 293 (3):755.