Xanthosine-5'-[(β,γ)-methyleno]triphosphate, Sodium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C11H17N4O14P3 (free acid)
Molecular Weight: 522.19 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: clear aqueous solution
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 276 nm, ε 9.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Fulga et al. (2001) SR beta coordinates signal sequence release from SRP with ribosome binding to the translocon. EMBO J. 20 (9):2338.
Legate et al. (2000) Nucleotide-dependent binding of the GTPase domain of the signal recognition particle receptor betasubunit to the alpha-subunit. J. Biol. Chem. 275 (35):27439.
Sakash et al. (2000) The use of nucleotide analogs to evaluate the mechanism of the heterotropic response of Escherichia coli aspartate transcarbamoylase. Protein Sci. 9 (1):53.
Hwang et al. (1999) Structure-based identification of a novel NTPase from Methanococcus jannaschii. Nat. Struct. Biol. 6 (7):691.
Muraoka et al. (1999) Effects of purinenucleotide analogues on microtubule assembly. Cell Struct. Funct. 24 (5):305.
Seifert et al. (1999) Effects of guanine, inosine, and xanthine nucleotides on beta (2)-adrenergic receptor/G (s) interactions: Evidence for multiple receptor conformations. Mol. Pharmacol. 56 (2):348.
Yu et al. (1997) Characterization of a Go alpha mutant that binds xanthine nucleotides. J. Biol. Chem. 272 (29):18015.
Rybin et al. (1996) GTPase activity of Rab5 acts as a timer for endocytic membrane fusion. Nature 383 (6597):266.
Powers et al. (1995) Reciprocal stimulation of GTP hydrolysis by 2 directly interacting GTPases. Science 269 (5229):1422.