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HckGST SH3 domain

Hematopoietic Tyrosine Kinase, SH3 domain

human, recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-336 50 μg 230,00 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Accession number: 5HCK

Accession number: 5HCK

Purity: > 90 % (SDS-PAGE)

Form: lyophilised

Description:
N-terminal GST tagged Hck SH3 domain. Hck SH3 domain is the SH3 domain of Hck tyrosine kinase. SH3 domains are known to bind proline rich peptides. The Hck SH3 domain has been expressed as a fusion protein with GST allowing expression in E. coli and purification by affinity chromatography. The native GST-Hck-SH3 is the ideal tool for in vitro/in vivo investigations of the behaviour of cellular prions. It may be used for protein-protein interaction studies as well as for in vitro/in vivo conversion studies. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.

Selected References:
Kuriyan et al. (1997) Modular peptide recognition domains in eukaryotic signaling. Ann. Rev. Biophys. Biomol. Struct. 26:259.