AMPK α1 (1-310) - inactive

AMPK-activated protein kinase

human, recombinant, E. coli

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AMPK α1 (1-310) - inactive PR-319 10 μg 491,05 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Molecular Weight: 63 kDa

Accession number: BC037303

Accession number: BC037303

Purity: > 60 % (SDS-PAGE)

Form: liquid (Supplied in 50 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, 0.05% Brij, 10% glycerol pH 7.5)

pH: 7.5

Description:
Purified human recombinant AMPK alpha1 subunit (amino acids 1-310) expressed in E.coli. Suitable for activation by LKB1. Features a GST-tag to facilitate removal of the enzyme from the reaction mixture. Purified by gluthathione sepharose affinity chromatography.

Selected References:
Hardie (2007). AMPK-activated protein kinase as a drug target. Annu Rev Pharmacol Toxicol 47:210.
Shimmak et al. (2006). Role in metabolism and therapeutic implications. Diabetes Obes Metab 8:602.
Marshal (2006). Role of insulin, adipocyte hormones and nutrient sensing pathways in regulating fuel metabolism and energy homeostasis: a nutritional perspective of diabetes, obesity and cancer. Sci STKE 7:341.