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Rab31GST-His

Ras-associated, small GTP-binding protein

human, recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-193 50 μg 212,18 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Molecular Weight: 26 kDa

Accession number: NP_006859

Accession number: NP_006859

Purity: > 90 % (SDS-PAGE)

Form: liquid (Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol)

Activity: 100 pmol of protein can bind > 80 pmol of GDP.

Description:
Rab31 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small Rab31 GTPase is associated with early endosomes and trans Golgi. It regulates biosynthetic pathways from endosomes to Golgi. It plays an important role in phagosome maturation. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.

Selected References:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071.
Yamaguchi et al. (2002) A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc. Natl. Acad. Sci. USA. 99:14536.