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Rab19GST-His

Ras-associated, small GTP-binding protein

mouse, recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-189 50 μg 212,18 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Accession number: NP_035356

Accession number: NP_035356

Purity: > 90 % (SDS-PAGE)

Form: liquid (Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol)

Activity: 100 pmol of protein can bind > 80 pmol of GDP.

Description:
Rab19 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab 19 is expressed at high levels in intestine, lung and spleen, and at a lower level in kidne. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.

Selected References:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071.
Mohrmann et al. (2002) Rab4 function in membrane recycling from early endosomes depends on a membrane to cytoplasm cycle. J. Biol. Chem. 277:32029.
Somsel et al. (2000) Rab GTPases coordinate endocytosis. J. Cell Sci. 113:183.