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Rab1BGST-His

Ras-associated, small GTP-binding protein

rat, recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-114 50 μg 212,18 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Molecular Weight: 52 kDa

Accession number: X13905

Accession number: X13905

Purity: > 90 % (SDS-PAGE)

Form: liquid (Supplied in 50 mM Tris-HCl pH 8.0, 200 mM NaCl, 2 mM MgCl2, 10 μM GDP and 2 mM beta-mercaptoethanol)

Activity: 100 pmol of protein can bind > 80 pmol of GDP.

Description:
Rab1B is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. For example, Rab1A (cat.# PR-113), Rab1B, and Rab2 (cat.# PR-111, PR-112) are located in the ER to Golgi intermediate compartment and cis Golgi cisternae and are required for ER to Golgi and intra Golgi transport. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.

Selected References:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071.
Plutner et al. (1991) Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. J. Cell Biol. 115:31.
Jin et al. (1996) Rab1a and multiple other Rab proteins are associated with the transcytotic pathway in rat liver. J. Biol. Chem. 271:30105.