» Sign in / Register

IL-1 α

Interleukin-1 alpha

human, recombinant, E. coli

Product Cat. No. Amount Price (EUR) Buy / Note
IL-1 α PR-400 10 μg 460,00 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Accession number: X02531

Accession number: X02531

Purity: > 95 % (SDS-PAGE)

Form: liquid (Supplied in PBS containing 50 μg BSA/μg IL-1β)

Interleukins-1 (IL-1) α and β belong to the family of regulatory and inflammatory cytokines which play an important role in the regulation of acute inflammation. IL-1α stimulates bone resorption, nuclear phospholipase C, and induces nitric oxide synthase. The closely related proteins IL-1α and IL-1β share approximately 62% homology in amino acid sequence but exhibit nearly identical biochemical action.

Selected References:
Bazan et al. (1996) A newly defined Interleukin-1. Nature 379:591.
Arend et al. (1998) Interleukin-1 receptor antgonist - role in biology. Annu. Rev. Immunol. 16:27.
Dunn (2002) Mechanisms by which cytokines signal the brain. Neurobiology of the Immune System 52:43.