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Interferon-Alpha 1 human

human, recombinant, E. coli

Product Cat. No. Amount Price (EUR) Buy / Note
IFN a PR-450 10 μg 253,00 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
avoid freeze/thaw cycles
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA)

Shelf Life: 12 months

Molecular Weight: 20 kDa

Accession number: P05011

Accession number: P05011

Purity: > 95 % (SDS-PAGE, RP-HPLC)

Form: liquid (Supplied in PBS pH 7.4)

pH: 7.4

Interferons are cytokines that are widely known to induce potent anti-viral activity. Interferon -α exerts a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFNA1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 167 amino acids and having a molecular mass of 19.5 kDa. The IFN-alpha 1 is purified by proprietary chromatographic techniques.

Selected References:
Birk et al. (2006) IFN-alpha induces apoptosis of adipose tissue cells. Biochem Biophys Res Commun. 345:669.
Luft et al. (2002)IFN-alpha enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells. Int Immunol. 14:367.
Liu et al. (2001) High-yield expression and purification of human interferon alpha-1 in Pichia pastoris. Protein Expr Purif. 22:381.