Prion Protein, cellular form
mouse, recombinant, E. coli
| Cat. No. | Amount | Price (EUR) | Buy / Note |
|---|---|---|---|
| PR-910 | 5 μg | 241,40 | Add to Basket/Quote Add to Notepad |
For in vitro use only!
Shipping: shipped on dry ice
Storage Conditions: store at -80 °C
avoid freeze/thaw cycles
Shelf Life: 12 months
Accession number: NM_011170 / P04925
Purity: > 90 % (SDS-PAGE)
Form: liquid (Supplied in 10 mM sodium acetate pH 4.5 and 0.02 % sodium azide)
Description:
N-terminal His-tagged full-length prion protein (PrPc). The PrPc -like conformation of the protein after refolding procedure was confirmed by high resolution NMR spectroscopy. The native His tagged PrPc is the ideal tool for in vitro/in vivo investigations of the behaviour of cellular prions. It may be used for protein-protein interaction studies as well as for in vitro/in vivo conversion studies.
Selected References:
Prusiner (1998) Prions. Proc. Natl. Acad. Sci. USA 95:13363.
Pan et al. (1993) Conversion of α-helices into β-sheets features in the formation of the scrapie prion proteins. Proc. Natl. Acad. Sci. USA 90:10962.
Lee et al. (1998) Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Res. 8:1022.
