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PrPc (wild type)His

Prion Protein, cellular form

bovine, recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-370 50 μg 201,25 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped at ambient temperature

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Accession number: AB001468

Accession number: AB001468

Purity: > 95 % (SDS-PAGE)

Form: lyophilised (lyophilised from 10 mM Tris-HCl pH 6.7)

N-terminal His-tagged full-length mature PrPc. The protein may be reconstituted in detergent-containing buffers e.g. TX-100 (0.5%) or under mild denaturing conditions (e.g. 1.5 M guanidine-HCl or urea). The His-PrPc is an ideal positive control in immunochemical detection of prions. It may be used directly for the production of antibodies in animals.

Selected References:
Prusiner (1998) Prions. Proc. Natl. Acad. Sci. USA 95:13363.
Pan et al. (1993) Conversion of α-helices into β-sheets features in the formation of the scrapie prion proteins. Proc. Natl. Acad. Sci. USA 90:10962.
Lee et al. (1998) Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Res. 8:1022.