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Immobilized 2'/3'-EDA-m7GTP

2'/3'-EDA-m7GTP-Agarose

2'/3'-EDA-7-Methyl-guanosine 5'-triphosphate (2'/3'-EDA-m7GTP) immobilized on Agarose

Cat. No. Amount Price (EUR) Buy / Note
AC-142S 1 ml 223,86 Add to Basket/Quote Add to Notepad
AC-142L 5 ml 895,45 Add to Basket/Quote Add to Notepad
Structural formula of Immobilized 2'/3'-EDA-m7GTP (2'/3'-EDA-m7GTP-Agarose)
Structural formula of Immobilized 2'/3'-EDA-m7GTP

For research use only!

Shipping: shipped at 4 °C

Storage Conditions: store at 4 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Degree of substitution: 5 μmol - 7 μmol 2'/3'-EDA-m7GTP/ml gel

Storage buffer: 20% Ethanol

Product Citations:
Please click the black arrow on the right to expand the citation list. Click publication title for the full text.

Selected References:
Zhu et al. (2019) Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells. Cell Death Dis. 10 (2):118.
Zhu et al. (2019) XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis. Cell Death Dis. 10 (6):395.
William et al. (2018) eIF4E-Binding Proteins 1 and 2 Limit Macrophage Anti-Inflammatory Responses through Translational Repression of IL-10 and Cyclooxygenase-2. J. Immunol. doi:10.4049.
Posternak et al. (2017) MYC Mediates mRNA Cap Methylation of Canonical Wnt/β-catenin Signaling Transcripts by Recruiting CDK7 and RNA Methyltransferase. Mol. Cancer Res. 15 (2):213.
Xu et al. (2016) Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome. BMC Genomics 17:25.
Liberman et al. (2015) DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation. Nucleic Acids Res. 43 (7):3764.