Small GTPases of the Ras superfamily are key regulators of numerous essential cellular processes, including signal transduction, vesicle trafficking, cytoskeleton organization, and cell proliferation. Mutations and dysregulation of these proteins are closely linked to oncogenesis and a variety of human diseases, making them highly relevant targets in molecular and biomedical research.
Our portfolio includes recombinant small GTPases from the Ran, Rab, and Rho/Rac/Cdc42 families, produced under controlled conditions for reliable experimental performance.
Rab family proteins represent the largest branch of the Ras superfamily and regulate vesicular trafficking pathways as membrane-associated molecular switches.
Ran family proteins are involved in nucleo-cytoplasmic transport, mitotic spindle assembly, and nuclear organization.
Rho/Rac/Cdc42 family proteins play central roles in cytoskeleton organization, cell migration, signaling pathways, and processes associated with tumor development and progression.
