The term GTPase, GTP-binding protein - or simply G-protein - is used for enzymes that are involved in cellular signal transduction by utilizing the nucleotide GTP.
GTP-binding proteins and their regulatory factors are central components of cellular signal transduction pathways, controlling processes such as cell growth, migration, vesicle transport, and cytoskeleton organization. Dysregulation of these signaling pathways is closely associated with cancer and numerous other diseases.
Our portfolio of recombinant GTP signal transduction proteins includes key components involved in small GTPase signaling, including GEFs (guanine nucleotide exchange factors), GTPase effectors, and GTPase activity assays for functional analysis of signaling pathways.
Produced under controlled conditions, these products provide reliable performance for cell biology, biochemical, and molecular research applications.
