Ras-associated, small GTP-binding protein
mouse, recombinant, E. coli
For in vitro use only!
Shipping: shipped on dry ice
Storage Conditions: store at -80 °C
avoid freeze/thaw cycles
Shelf Life: 12 months
Molecular Weight: 52 kDa
Accession number: AF226873
Purity: > 90 % (SDS-PAGE)
Form: liquid (Supplied in 25 mM HEPES pH 7.2, 100 mM NaCl, 2 mM MgCl2, 10 μM GDP and 2 mM DTE)
Activity: 100 pmol of protein can bind > 80 pmol of GDP.
Rab1A is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. For example, Rab1A, Rab1B (cat.# PR-114), and Rab2 (cat.# PR-111, PR-112) are located in the ER to Golgi intermediate compartment and cis Golgi cisternae and are required for ER to Golgi and intra Golgi transport. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071.
Jin et al. (1996) Rab1a and multiple other Rab proteins are associated with the transcytotic pathway in rat liver. J. Biol. Chem. 271:30105.