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Biotin-labeled geranyl pyrophosphate, triethylammonium salt

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LI-015 20 μl 221,50 Add to Basket/Quote Add to Notepad
Structural formula of B-GPP (Biotin-labeled geranyl pyrophosphate, triethylammonium salt)
Structural formula of B-GPP

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Molecular Formula: C20H35N3O9P2S

Molecular Weight: 555.52 g/mol

Purity: mass identification conforms (ESI-MS)

Form: liquid (Supplied as 1 mM solution in 25 mM (NH4)2CO3)

Concentration: 1 mM

B-GPP is a biotin-labeled analog of geranyl pyrophosphate (GPP). It serves as lipid donor for the native RabGGTase and mutants of GGTase-I and FTase. B-GPP allows for straightforward mammalian prenylome labeling and thus, not only identifying protein prenyltransferase substrates but efficiently screening for new inhibitors.

BIOZ Product Citations:

Selected References:
Kovtun et al. (2010) Towards the construction of expressed proteomes using a Leishmania tarentolae based cell-free expression system. PLoS One. 5 (12):e14388.
Nguyen et al. (2009) Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nature Chemical Biology. 5 (4):227.