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8-Iodo-GppNHp

(8I-GppNHp, 8I-GMPPNP)

8-Iodo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-126 200 μl (10 mM) 899,93 Add to Basket/Quote Add to Notepad
Structural formula of 8-Iodo-GppNHp ((8I-GppNHp, 8I-GMPPNP), 8-Iodo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt)
Structural formula of 8-Iodo-GppNHp

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 6 months after date of delivery

Molecular Formula: C10H16N6O13P3I (free acid)

Molecular Weight: 648.09 g/mol (free acid)

Exact Mass: 647.90 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 261 nm, ε 17.9 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Schmohl et al. (2012) Functional analysis of Rho GTPase activation and inhibition in a bead-based miniaturized format. Methods. Mol. Biol. 827 : 271.
Labesse et al. (2011) Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation. Nucleic Acids Res. 39 (8):3458.
Ash et al. (2011) A suite of Switch I and Switch II mutant structures from the G-protein domain of FeoB Acta Crystallogr. D Biol. Crystallogr. 67 (11):973.