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Nucleotides labeled mit Ferrocene (Fe)

Ferrocene is used as gold standard for electrochemical labeling. Its conjugation at 7- position of 7-deaza-2'-deoxyadenosine triphosphate or 5- position of cytidine triphosphate allows enzymatic incorporation of such adenosine and cytidine triphosphate analogs in primer extension reactions and PCR. The compounds might be used for electrochemical redox labelling of DNA, site specific redox labelling or in development of highly sensitive genosensors.