3',5'-pppApp
Adenosine-3'-diphosphate-5'-triphosphate, Lithium salt
| Cat. No. | Amount | Price (EUR) | Buy / Note |
|---|---|---|---|
| NU-543S | 10 μl (100 mM) | 151,40 | Add to Basket/Quote Add to Notepad |
| NU-543L | 5 x 10 μl (100 mM) | 670,40 | Add to Basket/Quote Add to Notepad |
For general laboratory use.
Please centrifuge briefly before opening (volume ≤2 ml).
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C10H18N5O19P5 (free acid)
Molecular Weight: 667.14 g/mol (free acid)
Exact Mass: 666.93 g/mol (free acid)
Purity: ≥ 90 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 100 mM - 110 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 259 nm, ε 15.1 L mmol-1 cm-1 (Tris-HCl pH 7.5)
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BIOZ Product Citations:
Selected References:
Ahmad et al. (2019) An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp. Nature 575: 674.
Jimmy et al. (2020) A widespread toxin-antitoxin system exploiting growth control via alarmone signaling. Proc. Natl. Acad. Sci. U.S.A. 117: 10500.
Anderson et al. (2021) Regulatory Themes and Variations by the Stress-Signaling Nucleotide Alarmones (p)ppGpp in Bacteria. Annu Rev Genet. 55: 115.
Chau et al. (2021) Emerging and divergent roles of pyrophosphorylated nucleotides in bacterial physiology and pathogenesis. PLOS Pathogens 17(5): e1009532.
Steinchen et al. (2021) Dual Role of a (p)ppGpp‐and (p)ppApp‐degrading Enzyme in Biofilm Formation and Interbacterial Antagonism. Molecular Microbiology 115(6): 1339.
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