Negative control for 2',3'-cGAMP
Guanosine-(2'→5')-adenosine-3'-O-phosphate, Sodium salt
Gp(2'-5')Ap
| Cat. No. | Amount | Price (EUR) | Buy / Note |
|---|---|---|---|
| NU-460 | 1 μmol | 195,00 | Add to Basket/Quote Add to Notepad |
For general laboratory use.
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C20H26N10O14P2 (free acid)
Molecular Weight: 692.43 g/mol (free acid)
Exact Mass: 692.11 g/mol (free acid)
Purity: ≥ 98 % (HPLC) / ≤ 2.5 EU/ml Endotoxin (LAL test)
Form: solid (lyophilized from filtered (10 kDa) solution in water)
Color: white to off-white
Spectroscopic Properties: λmax 260 nm, ε 25.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Applications:
2’,5’-GpAp, also known as 2’,3’-cGAMP control, can be used as a negative control for 2’,3’-cGAMP due to its linear conformation.[1]
BIOZ Product Citations:
Selected References:
[1] Ablasser et al. (2013) cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. Nature 498(7454):380.
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