2-Amino-ATP

For general laboratory use.

Please centrifuge briefly before opening (volume ≤2 ml).

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C₁₀H₁₇N₆O₁₃P₃ (free acid)

Molecular Weight: 522.20 g/mol (free acid)

Exact Mass: 522.01 g/mol (free acid)

CAS#: 18549-34-3 (free acid)

Purity: ≥ 95 % (HPLC)

Form: solution in water

Color: colorless to slightly yellow

Concentration: 100 mM - 110 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λ_max 279 nm, ε 9.89 L mmol^-1 cm^-1 (Tris-HCl pH 7.5), λ_exc 280 nm, λ_em 350 nm

BIOZ Product Citations:

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Selected References:
Lei et al. (2017) Structure-activity relationships of the ATP cofactor in ligase-catalysed oligonucleotide polymerisations. Org. Biomol. Chem. 15 (11):2349.
Ehteshami et al. (2013) Formation of a Quaternary Complex of HIV-1 Reverse Transcriptase with a Nucleotide-competing Inhibitor and Its ATP Enhancer. J. Biol. Chem. 288 (24):17336.
Höbartner et al. (2007) Engineering a selective small-molecule substrate binding site into a deoxyribozyme. Angew. Chem. Int. Ed. Engl. 468 (39):7420.
Wigle et al. (2007) Conformationally selective binding of nucleotide analogues to Escherichia coli RecA: a ligand-based analysis of the RecA ATP binding site. Biochemistry 45 (14):4502.
Ward et al. (1969) Fluorescence studies of nucleotides and polynucleotides. I. Formycin, 2-aminopurine riboside, 2,6-diaminopurine riboside, and their derivatives. J. Biol. Chem. 244 (5):1228.