5-Methoxyuridine-5'-triphosphate, Sodium Salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C10H17N2O16P3 (free acid)
Molecular Weight: 514.17 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: clear aqueous solution
Concentration: 100 mM - 110 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 278 nm, ε 8.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)
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An et al. (2019) Long-term efficacy and safety of mRNA therapy in two murine models of methylmalonic acidemia. EBioMedicine 45:519.
Novakowski et al. (2019) Delivery of mRNA to platelets using lipid nanoparticles. Sci. Rep. 9 (1):552.
An et al. (2017) Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia. Cell Rep. 21 (12):3548.
Li et al. (2016) Effects of Chemically Modified Messenger RNA on Protein Expression Bioconjugate Chem. 27:849.