Biotin-11-ATP
For research use only.
Please centrifuge briefly before opening (volume ≤2 ml).
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C30H45N8O16P3S (free acid)
Molecular Weight: 898.71 g/mol (free acid)
Exact Mass: 898.19 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: filtered solution (30 kDa) in 10 mM Tris-HCl
Color: colorless to slightly yellow
Concentration: 1.0 mM - 1.1 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 280 nm, ε 12.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Selected References:
Chu et al. (2020) Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F. Cell Rep. 30 (8):2481.
Parida et al. (2019) Nucleotide Resolution Comparison of Transcription of Human Cytomegalovirus and Host Genomes Reveals Universal Use of RNA Polymerase II Elongation Control Driven by Dissimilar Core Promoter Elements. mBio 10 (1):e02047-18.
Mahat et al. (2016) Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq). Nat. Protoc. 11 (8):1455.
Nagarkatti et al. (2012) Development of an aptamer-based concentration method for the detection of Trypanosoma cruzi in blood. PLoS One 7 (8):e43533.
Mitobe et al. (2008) Involvement of RNA-binding protein Hfq in the post-transcriptional regulation of invE gene expression in Shigella sonnei. Int. J. Parasitol. 283 (9):5738.
Göringer et al. (2003) In vitro selection of high-affinity nucleic acid ligands to parasite target molecules. Int. J. Parasitol. 33 (12):1309.
| Cat. No. | Amount | Price |
|---|---|---|
| NU-957-BIOX-S | 10 μl (1 mM) | 133,00 € |
| NU-957-BIOX-L | 5 x 10 μl (1 mM) | 515,30 € |
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Scientific citations for Jena Bioscience nu-957-biox
2 scientific citations and 0 citation images found by Bioz.
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m 6 Am sequesters PCF11 to suppress premature termination and drive neuroblastoma differentiation.
Molecular cell, 2024-10-23 · PMID:39481383
Abstract: N 6 ,2'-O-dimethyladenosine (m 6 Am) is an abundant mRNA modification that impacts multiple diseases, but its function remains controversial because the m 6 Am reader is unknown. Using quantitative proteomics, we identified transcriptional terminator premature cleavage factor II (PCF11) as a m 6 Am-specific reader in human cells. Direct quantification of mature versus nascent RNAs reveals that m 6 Am does not regulate mRNA stability but promotes nascent transcription
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Nuclear export restricts Gdown1 to a mitotic function
Nucleic Acids Research, 2022-02-28 · PMID:35048979
containing nuclei were then resuspended in 300 μl storage buffer and frozen. PRO-Seq library preparation was carried out as previously described, with the exception that biotinylated nucleotides from
Jena Bioscience were utilized (Biotin-11-UTP, Jena NU-821-BIOX, Biotin-11-CTP Jena, NU-831-BIOX, Biotin-11-ATP, JenaNU-957-BIOX-L , Biotin-11-GTP, Jena NU-971-BIOX-L). Libraries were sequenced with 50
