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GTP - Solid - Purity 85 %

Guanosine 5'-triphosphate, Disodium salt trihydrate

Cat. No. Amount Price (EUR) Buy / Note
NU-1047-200 200 mg 48,50 Add to Basket/Quote Add to Notepad
NU-1047-1G 1 g 96,90 Add to Basket/Quote Add to Notepad
NU-1047-10G 10 g 258,10 Add to Basket/Quote Add to Notepad
NU-1047-100G 100 g 814,30 Add to Basket/Quote Add to Notepad
Structural formula of GTP - Solid - Purity 85 % (Guanosine 5'-triphosphate, Disodium salt trihydrate)
Structural formula of GTP - Solid - Purity 85 %

For research use only!

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C10H16N5O14P3 (free acid)

Molecular Weight: 523.18 g/mol (free acid)

Exact Mass: 522.99 g/mol (free acid)

CAS#: 56001-37-7

Purity: ≥ 85 % (HPLC)

Form: solid

Color: white to off-white

Spectroscopic Properties: λmax 252 nm, ε 14.2 L mmol-1 cm-1 (Tris-HCl pH 7.0)

Assembly of ribosomal units[1]
Microdomain formation by small GTPases[2]
Antiviral activity of large GTPases (dynamin superfamily)[3]
Regulation of exocytosis by Rho GTPases[4]
Mechanism of hydrolysis by ADP-ribosylation factors[5]

Specific Ligands:

Guanylate binding proteins[6]

Yeast septins[7]

Quality Control Specifications: in vitro transcription (T7 RNA polymerase): visible RNA fragments after 5 min incubation, DNases, RNases, Nicking Activity: not detectable, Proteases: not detectable

Selected References:
[1] Blombach et al. (2011) Assembling the archeal ribosome: roles for transition factor-related GTPases. Biochemical Society Transactions 39:45.
[2] Stuermer (2011) Microdomain-forming proteins and the role of the reggies/flottilins during axon regeneration in zebrafish. Biochimica Biophysica Acta, Molecular Basis of Disease 1812:415.
[3] Haller et al. (2011) Human MxA protein: An Interferon-induced Dynamin-like GTPase with broad antiviral activity. J. Interferon and Cytokine Research 31:79.
[4] Stephane et al. (2011) Rho GTPases and exocytosis: what are the molecular links? Seminars in Cell and Developmental Biology 22:27.
[5] East et al. (2011) Models for the function of Arf GAPs. Seminars in Cell and Developmentan Biology 22:3.
[6] Vestal et al. (2011) The guanylate binding proteins: Emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase. J. Interferon and Cytokine Research 31:89.
[7] Younghoon et al. (2011) Septin structure and function in yeast and beyond. Trends in Cell Biology 21:141.
Drummond et al. (2011) Reconstitution and Organization of Escherichia coli Proto-ring Elements (FtsZ and FtsA) inside Giant Unilamellar Vesicles Obtained from Bacterial Inner Membranes. Methods Mol. Biol. 777 :29.
Katsuki et al. (2011) Preparation of dual-color polarity-marked fluorescent microtubule seeds. Methods Mol. Biol. 777:117.
Ramachandran et al. (2009) Membrane Insertion of the Pleckstrin Homology Domain Variable Loop 1 Is Critical for Dynamin-catalyzed Vesicle Scission. Molecular Biology of the Cell 20 (22):4630.