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dTpCpp

(dTMPCPP)

2'-Deoxythymidine-5'-[(α,β)-methyleno]triphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-895S 50 μl (10 mM) 129,40 Add to Basket/Quote Add to Notepad
NU-895L 5 x 50 μl (10 mM) 379,00 Add to Basket/Quote Add to Notepad
Structural formula of dTpCpp ((dTMPCPP), 2'-Deoxythymidine-5'-[(α,β)-methyleno]triphosphate, Sodium salt)
Structural formula of dTpCpp

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C11H19N2O13P3 (free acid)

Molecular Weight: 480.20 g/mol (free acid)

Exact Mass: 480.01 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 267 nm, ε 9.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Gowda et al. (2012) Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases. Chem. Res. Toxicol. 25 (6):1195.
Beese et al. (1993) Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. Biochemistry 32 (51):14095.