2'NH₂-dUTP

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C₉H₁₆N₃O₁₄P₃ (free acid)

Molecular Weight: 483.16 g/mol (free acid)

Exact Mass: 482.98 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: solution in water

Color: colorless to slightly yellow

Concentration: 100 mM - 110 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λ_max 262 nm, ε 10.1 L mmol^-1 cm^-1 (Tris-HCl pH 7.5)

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Selected References:
Govindan et al. (2012) P2Y receptor subtypes evoke different Ca²⁺ signals in cultured aortic smooth muscle cells. Purinergic Signalling 8:763.
Lauridsen et al. (2012) Enzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers. ChemBioChem 13:19.
Kanwar et al. (2011) Chimeric aptamers in cancer cell-targeted drug delivery. Crit. Rev. Biochem. Mol. Biol. 46 (6):459.
Lin et al. (1994) Modified RNA sequence pools for in vitro selection. Nucleic Acids Research 22 (24):5229.