2'-O-Methyladenosine-5'-triphosphate, Sodium salt
For research use only!
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C11H18N5O13P3 (free acid)
Molecular Weight: 521.21 g/mol (free acid)
Exact Mass: 521.01 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 100 mM - 110 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 259 nm, ε 15.1 L mmol-1 cm-1 (Tris-HCl pH 7.0)
Inhibition of RNA polymerase
Sequence specific incorporation by RNAse P
Nucleotide specifity of CCA-adding enzyme
BIOZ Product Citations:
Please click the arrow on the right to expand the citation list. Click publication title for the full text.
 Aastroem et al. (2004) Acidity of secondary hydroxyls in ATP and adenosine analogues and the question of 2,3-hydrogen bond in ribonucleosides. J. Am. Chem. Soc. 126 (45):14710.
 Aivazashvill et al. (1977) ATP analogs in the RNA-polymerase reaction. Molecularnaya Biologiya (Moscow) 11 (4):854.
 Conrad et al. (1995) Enzymatic synthesis of 2-modified nucleic acids: identification of important phosphate and ribose moieties in RNase P substrates. Nucleic Acids Res. 23 (11):1845.
 Vaish et al. (2003) A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality. Biochemistry 42 (29):8842.
Fa et al. (2004) Expanding the substrate repertoire of a DNA polymerase by directed evolution. J. Am. Chem. Soc. 126 (6):1748.
Cho et al. (2003) Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection. RNA 9 (8):970.