For research use only!
Shipping: shipped at ambient temperature
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 24 months after date of delivery
Molecular Formula: C10H13N3O6
Molecular Weight: 271.23 g/mol
Exact Mass: 271.08 g/mol
Purity: ≥ 95 % (HPLC)
Form: white to off-white powder
Solubility: water, methanol
Spectroscopic Properties: λmax 280 nm, ε 7.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Metabolism of dC substituted at position 5
Incorporation into DNA
functional and conformational influence of cytosine modifications
 Schiesser (2013) Deamination, Oxidation, and C-C Bond Cleavage Reactivity of 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxycytosine. J. Am. Chem. Soc. 135:14593.
 Schroeder (2014) Synthesis of a DNA promoter segment containing all four epigenetic nucleosides: 5-Methyl-, 5-hydroxymethyl-, 5-formyl-, and 5-carboxy-2'-deoxycytidine. Angew. Chem. Int. Ed. 53: 315.
 Sumino (2008) Synthesis and properties of oligodeoxynucleotides containing 5-carboxy-2'-deoxycytidines. Bioorg. Med. Chem. Lett. 18:274.