» Sign in / Register

8-Oxo-2'-deoxyguanosine Kit

8-Hydroxy-2'-deoxyguanosine Kit

Cat. No. Amount Price (EUR) Buy / Note
NK-109 1 Kit 191,95 Add to Basket/Quote Add to Notepad
Structures of 8-Oxo-2'-deoxyguanosine analogs
Structures of 8-Oxo-2'-deoxyguanosine analogs

For in vitro use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C

Shelf Life: 12 months after date of delivery

Description:
8-Oxo-Guanosines are used for random mutagenesis of DNA. 8-Oxo-dGTP can be incorporated by PCR but hybridizes with Adenosine instead of Cytidine.

The 8-Oxo-2'-deoxyguanosine Kit contains a set of 4 typical 8-Oxo-2'-deoxyguanosine analogs (Nucleoside, 5'-Mono, Di- and Triphosphate).

Content:

8-Oxo-2'-Deoxy-Guanosine Analog Cat. No. Amount
8-Oxo-dG N-1045 1 mg
8-Oxo-dGMP NU-1153 50 μl (10 mM)
8-Oxo-dGDP NU-1158 50 μl (10 mM)
8-Oxo-dGTP NU-1117 50 μl (10 mM)

Selected References:
Kai et al. (2002) An oxidized nucleotide affects DNA replication through activation of protein kinases in Xenopus egg lysates. Nucl. Acids Res. 30 (2):569.
Canitrot et al. (2000) Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells. FASEB J. 14 (12):1765.
Nampalli et al. (2000) Efficient synthesis of 8-oxo-dGTP: A mutagenic nucleotide. Bioorg. Med. Chem. Lett. 10 (15):1677.