» Sign in / Register

7-Methyl-Guanosine Kit

Cat. No. Amount Price (EUR) Buy / Note
NK-108 1 Kit 189,11 Add to Basket/Quote Add to Notepad

Structures of 7-Methyl-Guanosine analogs

For in vitro use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C

Shelf Life: 12 months

7-Methyl-Guanosines are important for RNA research. In living cells, mRNA is blocked ('capped') with a 7-Methyl-GTP residue at the 5' end. This prevents RNA degradation by 5'-exonucleases.

The 7-Methyl-Guanosine Kit contains a set of 4 typical 7-Methyl-Guanosine analogs (Nucleoside, 5'-Mono, Di- and Triphosphate).

Kit Contents

7-Methyl-Guanosine Analog Cat. No. Amount
m7G N-1052 3 mg
m7GMP NU-1135 100 μl (10 mM)
m7GDP NU-1134 100 μl (10 mM)
m7GTP NU-1122 100 μl (10 mM)

Selected References:
Shen et al. (2001) Structural and thermodynamic behavior of eukaryotic initiation factor 4E in supramolecular formation with 4E-binding protein 1 and mRNA cap analogue, studied by spectroscopic Methods. Chem. Pharm. Bull. 49 (10):1299.
Carberry et al. (1989) A spectroscopic study of the binding of m7GTP and m7GpppG to human protein synthesis initiation factor 4E. Biochemistry 28 (20):8078.
Beemon et al. (1977) In vitro translation yields a possible Rous sarcoma virus src gene product. Proc. Natl. Acad. Sci. USA. 74 (8):3302.