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6-Methylthio-Inosine Kit

Cat. No. Amount Price (EUR) Buy / Note
NK-105 1 Kit 189,11 Add to Basket/Quote Add to Notepad

Structures of 6-Methylthio-Inosine analogs

For in vitro use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C

Shelf Life: 12 months

6-Methylthio-Inosines are structurally related to 6-Thio-GTP. 6-Thio-Guanosines are metabolites of Azathioprine, a drug used in the therapy of chronic inflammatory and auto-immune diseases. The immunosuppressive properties of Azathioprine are very likely caused by binding of 6-Thio-GTP to the GTPase Rac.

The 6-Methylthio-Inosine Kit contains a set of 4 typical 6-Methylthio-Inosine analogs. (5'-Mono, Di- and Triphosphate).

Kit Contents

6-Methylthio-Inosine Analog Cat. No. Amount
6-Methylthio-I N-1053 3 mg
6-Methylthio-IMP NU-1131 100 μl (10 mM)
6-Methylthio-IDP NU-1132 100 μl (10 mM)
6-Methylthio-ITP NU-1133 100 μl (10 mM)

Selected References:
Lavi et al. (1985) A rapid and sensitive high-performance liquid chromatographic assay for 6-mercaptopurine metabolites in red blood cells. Anal. Biochem. 144 (2):514.