For in vitro use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Shelf Life: 12 months
6-Methylthio-Inosines are structurally related to 6-Thio-GTP. 6-Thio-Guanosines are metabolites of Azathioprine, a drug used in the therapy of chronic inflammatory and auto-immune diseases. The immunosuppressive properties of Azathioprine are very likely caused by binding of 6-Thio-GTP to the GTPase Rac.
The 6-Methylthio-Inosine Kit contains a set of 4 typical 6-Methylthio-Inosine analogs. (5'-Mono, Di- and Triphosphate).
|6-Methylthio-Inosine Analog||Cat. No.||Amount|
|6-Methylthio-IMP||NU-1131||100 μl (10 mM)|
|6-Methylthio-IDP||NU-1132||100 μl (10 mM)|
|6-Methylthio-ITP||NU-1133||100 μl (10 mM)|
Lavi et al. (1985) A rapid and sensitive high-performance liquid chromatographic assay for 6-mercaptopurine metabolites in red blood cells. Anal. Biochem. 144 (2):514.