» Sign in / Register

6-Methylthio-Guanosine Kit

Cat. No. Amount Price (EUR) Buy / Note
NK-104 1 Kit 191,95 Add to Basket/Quote Add to Notepad
Structures of 6-Methylthio-Guanosine analogs
Structures of 6-Methylthio-Guanosine analogs

For in vitro use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C

Shelf Life: 12 months after date of delivery

Description:
6-Methylthio-Guanosines are structurally related to 6-Thio-GTP. 6-Thioguanosines are metabolites of Azathioprine, a drug used in the therapy of chronic inflammatory and auto-immune diseases. The immunosuppressive properties of Azathioprine are very likely caused by binding of 6-Thio-GTP to the GTPase Rac.

The 6-Methylthio-Guanosine Kit contains a set of 4 typical 6-Methylthio-Guanosine analogs (5'-Mono, Di- and Triphosphate).

Content:

6-Methylthio-Guanosine Analog Cat. No. Amount
6-Methylthio-G N-1042 3 mg
6-Methylthio-GMP NU-1128 100 μl (10 mM)
6-Methylthio-GDP NU-1129 100 μl (10 mM)
6-Methylthio-GTP NU-1130 100 μl (10 mM)

Selected References:
Nelson et al. (1977) Oxypurine and 6-thiopurine nucleoside triphosphate formation in human erythrocytes. Adv. Exp. Med. Biol. 76A:121.