For in vitro use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Shelf Life: 12 months after date of delivery
6-Methylthio-Guanosines are structurally related to 6-Thio-GTP. 6-Thioguanosines are metabolites of Azathioprine, a drug used in the therapy of chronic inflammatory and auto-immune diseases. The immunosuppressive properties of Azathioprine are very likely caused by binding of 6-Thio-GTP to the GTPase Rac.
The 6-Methylthio-Guanosine Kit contains a set of 4 typical 6-Methylthio-Guanosine analogs (5'-Mono, Di- and Triphosphate).
|6-Methylthio-Guanosine Analog||Cat. No.||Amount|
|6-Methylthio-GMP||NU-1128||100 μl (10 mM)|
|6-Methylthio-GDP||NU-1129||100 μl (10 mM)|
|6-Methylthio-GTP||NU-1130||100 μl (10 mM)|
Nelson et al. (1977) Oxypurine and 6-thiopurine nucleoside triphosphate formation in human erythrocytes. Adv. Exp. Med. Biol. 76A:121.