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N6-Benzylaminopurine riboside

N6-Benzyladenosine

9-(β-D-Ribofuranosyl)-6-benzylaminopurine

Cat. No. Amount Price (EUR) Buy / Note
N-1022 1 g 104,04 Add to Basket/Quote Add to Notepad
Structural formula of N6-Benzylaminopurine riboside (N6-Benzyladenosine, 9-(β-D-Ribofuranosyl)-6-benzylaminopurine)
Structural formula of N6-Benzylaminopurine riboside

For research use only!

Shipping: shipped at ambient temperature

Storage Conditions: store at 4 °C

Shelf Life: 24 months after date of delivery

Molecular Formula: C17H19N5O4

Molecular Weight: 357.36 g/mol

Purity: > 99 %

Form: solid

Spectroscopic Properties: λmax 269 nm, ε 20.5 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Applications:
Agonistic ligand, mainly for nucleoside receptor A1

Selected References:
Dolezal et al. (2007) Preparation, biological activity and endogenous occurrence of N6-benzyladenosines. Bioorg. Med. Chem. 15 (11):3737.
Jacobson (2001) Probing adenosine and P2 receptors: design of novel purines and nonpurines as selective ligands. Drug Development Res. 52:178.
Mlejnek (2001) Caspase inhibition and N6-benzyladenosine-induced apoptosis in HL-60 cells. J. Cell. Biochem. 83 (4):678.
Mlejnek et al. (2000) Induction of apoptosis in HL-60 cells by N (6)-benzyladenosine. J. Cell. Biochem. 77 (1):6.
Van Galen et al. (1994) A binding site model and structure-activity relationships for rat A3 adenosine receptor. Molecular Pharmacology 45:1101.