» Sign in / Register


(-)-6-(Methylamino)purine riboside

Cat. No. Amount Price (EUR) Buy / Note
N-1080 200 μl (1 mM) 41,36 Add to Basket/Quote Add to Notepad
Structural formula of N6-Methyl-adenosine ((-)-6-(Methylamino)purine riboside)
Structural formula of N6-Methyl-adenosine

For research use only!

Shipping: shipped at ambient temperature

Storage Conditions: store at 4 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 24 months after date of delivery

Molecular Formula: C11H15N5O4

Molecular Weight: 281.27 g/mol

CAS#: 1867-73-8

Purity: ≥ 95 % (HPLC)

Form: solution in DMSO

Concentration: 1 mM

Spectroscopic Properties: λmax 265 nm; ε 18.5 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Binding studies, physiological studies on cell cultures or tissues and in animal experiments.
Compound has highest activity to nucleoside receptor type A1 and a less extent to A2A and A3.

Usage: Dissolve stock solution with aqueous physiological buffer recommended for displacement studies, biochemical signal transduction studies or animal experiments.
To avoid biological effects of DMSO dilute the stock solutions with aqueous buffers to a content of DMSO below 1 %.

Please note: Stable in acidic and neutral buffer solutions for one day

Selected References:
Jacobson (2013) Structure based approaches to ligands for G-protein-coupled adenosine and P2Y receptors, from small molecules to nanoconjugates. J. Med. Chem. 56:3749.
Jacobson et al. (2003) Engineering of A3 Adenosine and P2Y Nucleotide Receptors and their ligands. Drug Development Res. 58:330.
Van Galen et al. (1994) A binding site model and structure-activity relationships for rat A3 adenosine receptor. Molecular Pharmacology 45:1101.