γ-Aminophenyl-Adenosine triphospate (AP-ATP) immobilized on Agarose
For research use only!
Shipping: shipped at 4 °C
Storage Conditions: store at 4 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Suitable for purification of ATP-binding proteins.
Degree of substitution: 20 μmol - 22 μmol AP-ATP/ml gel
Storage buffer: 20 % Ethanol
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Rachidi et al. (2014) Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection. Antimicrobial Agents and Chemotherapy 58:1501.
Wu et al. (2010) 6-Alkylsalicylic acid analogues inhibit in vitro ATPase activity of heat shock protein 90. Arch Pharm Res. 33 (12):1997.
Yu et al. (2010) Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochemical Pharmacology 79:542.
Dhillon et al. (2009) The C-terminus of Raf-1 acts as a 14-3-3-dependent activation switch. Cellular Signalling 21:1645.
Zhang et al. (2008) A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells. Molecular Cancer Therapeutics 7 (1):162.
Zitzler et al. (2008) Distinct binding sites for the ATPase and substrate-binding domain of human Hsp70 on the cell surface of antigen presenting cells. Molecular Immunology 45:3974.
Jeansonne et al. (2006) A rapid ATP affinity-based purification for the human non-receptor tyrosine kinase c-Src. Protein Expression and Purification 46:240.
Drewes et al. (1995) Microtubule-associated Protein/Microtubule Affinity-regulating Kinase (p110mark). J. Biol. Chem. 270 (13):7679.
Haystead et al. (1993) γ-phosphate linked ATP-Sepharose for the affinity purification of protein-kinases - rapid purification to homogeneity of sceletal-muscle mitogen-activated protein-kinase. Eur. J. Biochem. 214 (2):459.