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m27,3'-OGP3G (ARCA Cap Analog)


P1-(5'-(3'-O-methyl)-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate, Sodium salt

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Structural formula of m27,3'-OGP3G (ARCA Cap Analog) (m27,3'-OG(5')ppp(5')G)
Structural formula of m27,3'-OGP3G (ARCA Cap Analog)

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible. If stored as recommended, Jena Bioscience guarantees optimal performance of this product for 12 months after date of delivery.

Shelf Life: 12 months

Molecular Formula: C22H31N10O18P3 (free acid)

Molecular Weight: 816.46 g/mol (free acid)

CAS#: 400806-46-4 (acid), 400806-60-2 (Trisodium salt)

Purity: ≥ 98 % (HPLC)

Form: solid

Spectroscopic Properties: λmax 255 nm; ε 22.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Jemielity et al. (2003) Novel anti-reverse cap analogs with superior translational properties. RNA 9:1108.
Peng et al. (2002) Synthesis and application of a chain-terminating dinucleotide mRNA cap analog. Org. Lett. 4 (2):161.
Stepinski et al. (2001) Synthesis and properties of mRNAs containing the novel anti-reverse cap analogs 7-methyl (3'-O-methyl)GpppG and 7-methyl (3'-deoxy)GpppG. RNA 7:1486.