Xanthosine-5'-triphosphate, Triethylammonium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible. If stored as recommended, Jena Bioscience guarantees optimal performance of this product for 12 months after date of delivery.
Shelf Life: 12 months
Molecular Formula: C10H15N4O15P3 (free acid)
Molecular Weight: 524.16 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: clear aqueous solution, pH 7.5 ±0.5
Concentration: 100 mM - 110 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 276 nm; ε 9.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Inhibitor of adenylyl and guanylyl cyclase
Soluble guanylyl cyclase
 Spangler et al. (2011) Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2', (3')-substituted purine and pyrimidine nucleotides. J. Pharmacol. Exp. Ther. 336 (1):234.
 Chang et al. (2005) Nitric Oxide-dependent Allosteric Inhibitory Role of a Second Nucleotide Binding Site in Soluble Guanylyl Cyclase. J. Biol. Chem. 280 (12):11513.
Beste et al. (2012) Nucleotidyl cyclase activity of soluble guanylyl cyclase α1β1. Biochemistry 51 (1):194.
Spangler et al. (2011) Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2', (3')-substituted purine and pyrimidine nucleotides. J Pharmacol Exp. Ther. 336 (1):234.
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Hwang et al. (1999) Structure-based identification of a novel NTPase from Methanococcus jannaschii. Nat. Struct. Biol. 6 (7):691.
Muraoka et al. (1999) Effects of purinenucleotide analogues on microtubule assembly. Cell Struct. Funct. 24 (5):305.
Seifert et al. (1999) Effects of guanine, inosine, and xanthine nucleotides on beta (2)-adrenergic receptor/G (s) interactions: Evidence for multiple receptor conformations. Mol. Pharmacol. 56 (2):348.
Yu et al. (1997) Characterization of a Go alpha mutant that binds xanthine nucleotides. J. Biol. Chem. 272 (29):18015.
Rybin et al. (1996) GTPase activity of Rab5 acts as a timer for endocytic membrane fusion. Nature 383 (6597):266.
Powers et al. (1995) Reciprocal stimulation of GTP hydrolysis by 2 directly interacting GTPases. Science 269 (5229):1422.