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dATPαS

2'-Deoxyadenosine-5'-(α-thio)-triphosphate, Sodium salt; (1 : 1 Mixture of Rp and Sp isomers)

Product Cat. No. Amount Price (EUR) Buy / Note
dATPαS NU-426S 100 μl (10 mM) 124,37 Add to Basket/Quote Add to Notepad
dATPαS NU-426L 5 x 100 μl (10 mM) 364,30 Add to Basket/Quote Add to Notepad

Structural formula of dATPαS

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible. If stored as recommended, Jena Bioscience guarantees optimal performance of this product for 12 months after date of delivery.

Shelf Life: 12 months

Molecular Formula: C10H16N5O11P3S (free acid)

Molecular Weight: 507.24 g/mol (free acid)

CAS#: 64145-28-4

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution, pH 7.5 ±0.5

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 259 nm; ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Gaur et al. (1993) Enzymatic RNA synthesis with deoxynucleoside 5'-O- (1-thiotriphosphates). FEBS Lett. 315 (1):56.
Abbotts et al. (1988) Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Effect of template sequence and substrate variation on termination of synthesis. J. Biol. Chem. 263 (29):15094.
Nakamaye et al. (1988) Direct sequencing of polymerase chain reaction amplified DNA fragments through the incorporation of deoxynucleoside alpha-thiotriphosphates. Nucleic Acids Res. 16 (21):9947.
Nyren et al. (1997) Detection of single-base changes using a bioluminometric primer extension assay. Anal. Biochem. 244 (2):367.