2',2'-Difluorocytidine-5'-triphosphate, Sodium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C9H14N3O13P3F2 (free acid)
Molecular Weight: 503.14 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: clear aqueous solution, pH 7.5 ±0.5
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 271 nm; ε 9.1 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Influence on epigenetic markers
Treatment of hepatocellular carcinoma
Treatment of bladder carcinoma
Treatment of lung cancer
Treatment of breast cancer
Treatment of ovarien cancer
 Dhayat et al. (2011) Epigenetic markers for chemosensitivity and chemoresistance in pancreatic cancer- A review. International J. of Cancer 129:1031.
 Chua et al. (2011) Targeted therapy in hepatocellular carcinoma. International J. Hepathology 348297:11.
 Shelly et al. (2011) Gemcitabine chemotherapy for treatment of metastatic bladder carcinoma. BJU International 108:168.
 Hayashi et al. (2011) Gemcitabine:efficacy in the treatment of advanced stage nonsquamous non-small cell lung cancer. Clinical Medicine Insights: Oncology 5:177.
 Moen et al. (2005) Gemcitabine: in combination with paclitaxel in the first line traetment of metastatic breast cancer. American J. of Cancer 4:327.
 Bookmann (2005) Gemcitabine monotherapy in recurrent ovarian cancer: from the bench to the clinic. International J. of Gynecological Cancer 15 Suppl.1:12.