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8-Bromo-adenosine-3',5'-cyclic monophosphate, Sodium salt

Product Cat. No. Amount Price (EUR) Buy / Note
8-Bromo-cAMP NU-1502S 10 mg 112,80 Add to Basket/Quote Add to Notepad
8-Bromo-cAMP NU-1502L 50 mg 330,42 Add to Basket/Quote Add to Notepad

Structural formula of 8-Bromo-cAMP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible. If stored as recommended, Jena Bioscience guarantees optimal performance of this product for 12 months after date of delivery.

Shelf Life: 12 months

Molecular Formula: C10H11N5O6PBr (free acid)

Molecular Weight: 408.10 g/mol (free acid)

CAS#: 76939-46-3

Purity: ≥ 95 % (HPLC)

Form: lyophilized

Spectroscopic Properties: λmax 264 nm; ε 17.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Paz et al. (1999) Corticotropin increases protein tyrosine phosphatase activity by a cAMP-dependent mechanism in rat adrenal gland. Eur. J. Biochem. 265:911.
Martin et al. (1999) Comparison of expression and regulation of the high-density lipoprotein receptor SR-BI and the lowdensity lipoprotein receptor in human adrenocortical carcinoma NCI-H295 cells. Eur. J. Biochem. 261:481.
Chen et al. (1998) Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas. Lab. Invest. 78:165.
Hei et al. (1991) Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs. Mol. Pharmacol. 39:233.
Malgaroli et al. (1989) Control of cytosolic free calcium in rat and chicken osteoclasts. The role of extracellular calcium and calcitonin. J. Biol. Chem. 264:14342.
Schubart et al. (1977) Cyclic adenosine 3':5'-monophosphate-mediated insulin secretion and ribosomal protein phosphorylation in a hamster islet cell tumor. J. Biol. Chem. 252:92.
Martin et al. (1981) Growth inhibition by adenosine 3',5-monophosphate derivatives does not require 3',5' phosphodiester linkage. Science 213:1120.
Meyer et al. (1974) Analogs of cyclic AMP and cyclic GMP: general methods of synthesis and the relationship of structure to enzymic activity. Life Sci. 14:1019.