» Sign in / Register

6-Mercaptopurine-riboside-5'-monophosphate

6-Thio-Inosine-5'-monophosphate

6-Mercaptopurine-riboside-5'-monophosphate, Sodium salt

Product Cat. No. Amount Price (EUR) Buy / Note
6-Mercaptopurine-riboside-5'-monophosphate NU-1148S 100 μl (10 mM) 112,80 Add to Basket/Quote Add to Notepad
6-Mercaptopurine-riboside-5'-monophosphate NU-1148L 5 x 100 μl (10 mM) 330,42 Add to Basket/Quote Add to Notepad

Structural formula of 6-Mercaptopurine-riboside-5'-monophosphate

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible. If stored as recommended, Jena Bioscience guarantees optimal performance of this product for 12 months after date of delivery.

Shelf Life: 12 months

Molecular Formula: C10H13N4O7PS (free acid)

Molecular Weight: 364.26 g/mol (free acid)

CAS#: 53-83-8

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution, pH 7.5 ±0.5

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 322 nm; ε 27.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Neurath et al. (2005) 6-Thioguanosine Diphosphate and Triphosphate Levels in Red Blood Cells and Response to Azathioprine Therapy in Crohn’s Disease. Clinical Gastroenterology and Hepatology 3 (10): 1007.
Wielinga et al. (2002)Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. Mol Pharmacol. 62 (6):1321.
Szabados et al. (1994) 5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRFCEM leukemia cells: purification, pH dependence, and inhibitors. Biochemistry 33 (47):14237.
Stet et al. (1993) A biochemical basis for synergism of 6-mercaptopurine and mycophenolic acid in Molt F4, a human malignant T-lymphoblastic cell line. Biochim Biophys Acta. 1180 (3):277.
Drake et al. (1982) Metabolism and mechanisms of action of 9- (tetrahydro-2-furyl)-6-mercaptopurine in Chinese hamster ovary cells. Chem Biol Interact. 41 (1):105.