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6-Mercaptopurine-riboside-5'-triphosphate

6-Thio-Inosine-5'-triphosphate

6-Mercaptopurine-riboside-5'-triphosphate, Sodium salt

Product Cat. No. Amount Price (EUR) Buy / Note
6-Mercaptopurine-riboside-5'-triphosphate NU-1110S 100 μl (10 mM) 112,80 Add to Basket/Quote Add to Notepad
6-Mercaptopurine-riboside-5'-triphosphate NU-1110L 5 x 100 μl (10 mM) 330,42 Add to Basket/Quote Add to Notepad

Structural formula of 6-Mercaptopurine-riboside-5'-triphosphate

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible. If stored as recommended, Jena Bioscience guarantees optimal performance of this product for 12 months after date of delivery.

Shelf Life: 12 months

Molecular Formula: C10H15N4O13P3S (free acid)

Molecular Weight: 524.22 g/mol (free acid)

CAS#: 27652-34-2

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution, pH 7.5 ±0.5

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 322 nm; ε 27.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Applications:
Competitive inhibitor of T4 RNA ligase[1]
Kinetic parameters with thiopurine methyltransferase[2]
Interaction with (sodium-potassium ion)-dependent ATPase[3]

Selected References:
[1] Labeikyte et al. (1995) Structural features of nucleotide binding in T4 RNA ligase determined from inhibition by structural analogs of ATP. Biologija 3:13.
[2] Deininger et al. (1994) Purine substrates for human thiopurine methyltransferase. Biochemical Pharmacology 48:2135.
[3] Erdmann et al. (1976) The cardiac glycoside receptor: its properties and its correlation to nucleotide binding sites, phosphointermediate, and Na-K-dependent ATPase activity. Recent Adv. Stud. Cardiac Struct. Metab. 9:329.
Bierau et al. (2007) Pharmacogenetic significance of inosine triphosphatase. Pharmacogenomics 8 (9):1221.
Patzelt et al. (1974) Study of (Na+K)-ATPase with 6-chloropurine triphosphate, 6-mercaptopurine triphosphate and dinitrophenyl-6-thiopurine triphosphate. H-S Z. Physiol. Chem. 355 (10):1237.