Quantifoil Micro Tools pioneered the commercialization of perforated support films with convenient predefined hole size, shape and arrangement for electron microscopy. Now, with more than 20 film geometries on a full range of TEM grid materials and designs, this diverse range of support foils provides high performance and flexibility whatever your cryo-EM research needs. The growing product portfolio encompasses UltrAuFoil® Holey Gold supports for high-throughput, high-resolution SPA, robust supports with larger open viewing areas for FIB-milling and tomography, and finder grids for CLEM and other integrative methods.
The surfactant Amphipol A8-35 stabilizes membrane proteins in a detergent-free aqueous solution and is a useful additive for sample preparation in Cryo-EM.
Cryo-EM Grid Selector
Select the required grid parameters and immediately retrieve the matching grid of interest!
[1] Glaeser (2016) How good can cryo-EM become? Nature Methods 13:28.
[2] Beniac et al. (2017) Structure of the Ebola virus glycoprotein spike within the virion envelope at 11 Å resolution. Sci. Rep. DOI: 10.1038/srep46374.
[3] Lokareddy et al. (2017) Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation. Nat. Commun. DOI: 10.1038/ncomms14310.