Optimization & Phasing

Initial crystallization hits often require careful follow-up optimization before they can be turned into diffraction-quality crystals. Jena Bioscience offers a focused range of products to refine crystallization conditions, improve crystal quality, support membrane protein crystallization, visualize crystals, and assist with phasing strategies.

Explore tools for optimizing the chemical environment, influencing nucleation and crystal growth, working with challenging membrane protein targets, identifying crystals, validating workflows with model proteins, and preparing crystals for structure determination.

Chemical Environment

Optimize buffer pH, precipitants, salts, additives, and other reagent components to refine initial crystallization hits and improve crystal quality.

Thermodynamics / Kinetics

Tools for influencing nucleation, crystal growth, solvent content, and seeding strategies to improve reproducibility and diffraction behavior.

Membrane Proteins

Products supporting the crystallization of challenging membrane protein targets, including lipidic cubic phase and specialized crystallization workflows.

Crystal Dyes

Crystal dyes help distinguish protein crystals from salt crystals and support fast visual inspection during screening and optimization.

Model Proteins

Model proteins provide reliable reference systems for crystallization training, method development, assay validation, and quality control.

Phasing

Reagents and tools for experimental phasing strategies to support structure solution when molecular replacement is not sufficient.